They have been incriminated in infections such as bacteremia, meningitis, pneumonia, urinary tract infections, surgical site infections, wound infections, osteomyelitis etc. In recent years due to the indiscriminate use of antimicrobials, NFGNB have emerged as important health care associated pathogens. Infections caused by other species are relatively infrequent. Currently Pseudomonas aeruginosa and Acinetobacter baumannii are the most commonly isolated nonfermenters pathogenic for humans. This heterogeneous group includes organisms like Pseudomonas.spp, Acinetobacter.spp, Alkaligenes.spp, Stenotrophomonas maltophilia, Burkholderia cepacia complex (BCC). Inherent resistance of these bacterial agents to commonly used disinfectants and there tendency to colonize various surfaces have been pivotal in their emergence as important nosocomial pathogens NFGNB are known to account for 15% of all bacterial isolates from clinical microbiological laboratory. They are saprophytic in nature but can cause a significant number of infections particularly in hospitalized patients, immunocompromised hosts and patients with hematological malignancies. Available from: Īerobic non fermenting gram negative bacilli (NFGNB) are a taxonomically diverse group of organisms that either do not utilize glucose as a source of energy or utilize it oxidatively. Prevalence of non-fermenting gram negative bacilli and their in vitro susceptibility pattern in a tertiary care hospital of Uttarakhand: A study from foothills of Himalayas.
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How to cite this URL: Juyal D, Prakash R, Shanakarnarayan SA, Sharma M, Negi V, Sharma N. How to cite this article: Juyal D, Prakash R, Shanakarnarayan SA, Sharma M, Negi V, Sharma N. Keywords: Acinetobacter, antibiotics, nonfermenters, nosocomial infection, Pseudomonas Improved antibiotic stewardship and infection-control measures will be needed to prevent or slow the emergence and spread of multidrug-resistant NFGNB in the healthcare setting. Conclusion: Identification of NFGNB and monitoring their susceptibility patterns will help in proper management of infections caused by them. Overall imipenem resistance was found to be 30.54%. Imipenem and amikacin were the drugs with maximum activity. A high level of antibiotic resistance was recorded for most of the first and second line drugs. Pseudomonas species (49.59%) and Acinetobacter species (43.09%) were the most commonly isolated NFGNB. Results: Among 2585 clinical samples 241 yielded NFGNB accounting for an isolation rate of 9.32% and a total of 246 non fermenters were grown as five samples yielded two types of NFGNB. Antimicrobial susceptibility testing was performed by Kirby Bauer disc diffusion method. Non fermenters were identified using a standard protocol. Materials and Methods: A total of 2585 various clinical specimens were received in laboratory and were processed. Aim of the present study was to characterize the prevalence of NFGNB along with their antimicrobial sensitivity pattern among the patients coming to our hospital a tertiary care center. Prevalence and antibiogram of NFGNB has not yet been reported from this part of India. Identification of NFGNB and monitoring their susceptibility pattern are important for proper management of infections caused by them. Introduction: Non-fermenting gram negative bacilli (NFGNB) are taxonomically diverse group of pathogens that has emerged as a major cause of health care associated infections especially in immunocompromised hosts.
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